Osivir Infusion 500mg is a potent antiviral medication delivered via intravenous infusion. Each single-dose vial contains 500mg of Aciclovir, specifically formulated for serious viral infections requiring immediate and direct administration into the bloodstream. Uses Osivir Infusion 500mg is indicated for severe herpes simplex infections, initial and recurrent genital herpes in immunocompromised patients, herpes simplex encephalitis, severe initial genital herpes, herpes zoster infections in immunocompromised patients, and varicella (chickenpox) infections in immunocompromised patients. Benefits Rapid delivery of medication directly to bloodstream Effective against severe viral infections Appropriate when oral therapy isn’t suitable Provides treatment option for immunocompromised patients Helps prevent viral replication and spread Reduces duration and severity of symptoms Decreases risk of complications from severe infections Effective for CNS herpes infections How It Works Osivir Infusion 500mg contains Aciclovir, which is converted to aciclovir triphosphate inside virus-infected cells. This active form inhibits viral DNA polymerase, preventing viral DNA synthesis and replication, thereby stopping the spread of infection while allowing the immune system to clear infected cells. Duration of Action Intravenous Aciclovir reaches peak plasma concentrations immediately after infusion. The elimination half-life is approximately 2-3 hours in patients with normal renal function, with antiviral activity continuing for 4-8 hours after administration. Dosage Patient Group Recommended Dosage Frequency Adults (normal renal function) 5-10 mg/kg Every 8 hours Children 3 months-12 years 250-500 mg/m² Every 8 hours Neonates 10-20 mg/kg Every 8 hours Renal impairment Adjusted dose Extended interval Warnings Osivir Infusion 500mg must be administered by slow intravenous infusion over at least 1 hour to avoid renal tubular damage. Rapid or bolus injection must be avoided. Adequate hydration is essential during treatment. Renal function should be monitored before and during therapy. Side Effects Common side effects include phlebitis or inflammation at the injection site, transient increases in liver enzymes, and reversible increases in blood urea and creatinine. Less common effects include nausea, vomiting, headache, skin rashes, and rarely, neurological reactions such as tremors or confusion. Pregnancy and Breastfeeding Osivir Infusion 500mg should be used during pregnancy only when the potential benefits outweigh possible risks to the fetus. Use during breastfeeding requires careful consideration as Aciclovir passes into breast milk in small amounts. Interactions Nephrotoxic drugs (increased risk of renal impairment) Probenecid (decreased Aciclovir elimination) Mycophenolate mofetil (increased levels of both drugs) Theophylline (potential increased theophylline levels) Zidovudine (increased risk of neurological adverse effects) Cimetidine (increased Aciclovir plasma levels) Precautions For intravenous use only. Reconstitute and dilute according to instructions before administration. Administer by slow intravenous infusion only. Maintain adequate hydration. Monitor renal function. Discontinue immediately if signs of hypersensitivity occur. Dispose of unused portion of the single-dose vial. Important Information Osivir Infusion 500mg is for hospital use only. Administration should be supervised by healthcare professionals experienced in the use of antiviral therapy. The solution should be freshly prepared and used within 12 hours. This medication should be part of a comprehensive treatment approach for severe viral infections. Product Image Highlights Customer questions & answers Have a question about this product? Your question * Name * Email * Notify me when answered. Recent Popular Unanswered There are no questions yet. Be the first to ask a question about this product. Selected with You in Mind Ranbaxy Aciclovir 200mg Tablet x25₦17,000.00Rated 0 out of 5 Ranbaxy Aciclovir 200mg Tablet is used to treat infections caused... Add to cart Amantadine 100mg Tablet (Am-dine) x20₦27,000.00Rated 0 out of 5 Amantadine 100mg treats Parkinson's disease symptoms like tremors, stiffness, and movement difficulties.... Add to cart Alfavir Tablet 25mg (Tenofovir) x10₦20,000.00Rated 0 out of 5 Alfavir Tablet 25mg is used to treat HIV-1 infection in... Add to cart Sun Aciclovir 400mg Tablet x56₦24,500.00Rated 0 out of 5 Sun Aciclovir 400mg treats and prevents viral infections caused by... Add to cart Cancel replyReview our product to get a chance to receive coupon!Your email address will not be published. Required fields are marked *Your rating Rate… Perfect Good Average Not that bad Very poor Your review * Choose pictures & videos(maxsize: 2000 KB, max files: 5) Choose pictures & videos Your review is being submitted. Please wait a moment Name * Email * Save my name, email, and website in this browser for the next time I comment.
