Diatab Tablet 5mg contains Glibenclamide, a sulfonylurea antidiabetic medication. This oral hypoglycemic agent effectively lowers blood glucose levels in patients with type 2 diabetes mellitus by stimulating insulin release from pancreatic beta cells. Uses Diatab Tablet treats type 2 diabetes mellitus when diet and exercise alone are insufficient to control blood glucose levels. It’s prescribed for patients with functioning pancreatic beta cells who require medication to maintain normal blood sugar levels alongside lifestyle modifications. Benefits Effectively lowers blood glucose levels Stimulates natural insulin production Reduces risk of diabetic complications Improves glucose tolerance and control Helps maintain target HbA1c levels Reduces symptoms of hyperglycemia Can be combined with other diabetes medications Supports long-term diabetes management Cost-effective treatment option How It Works Diatab stimulates insulin release from pancreatic beta cells by blocking ATP-sensitive potassium channels. This action causes cell membrane depolarization, opening calcium channels and triggering insulin secretion. The medication also increases peripheral tissue sensitivity to insulin, improving glucose uptake and utilization. Dosage Patient Category Initial Dosage Maximum Daily Dosage Adults 2.5-5mg once daily 15mg daily (divided) Elderly 2.5mg once daily 10mg daily Take Diatab with breakfast or the first main meal to reduce hypoglycemia risk. Dosage adjustments should be made gradually based on blood glucose monitoring. Duration of Action Diatab begins working within 1-2 hours of administration, with peak effects occurring at 2-4 hours. The glucose-lowering effect lasts 12-24 hours, allowing once or twice-daily dosing. Regular blood glucose monitoring helps determine optimal timing and effectiveness. Side Effects Common side effects include hypoglycemia, weight gain, and mild gastrointestinal upset. Some patients experience dizziness, headache, or skin reactions. Severe hypoglycemia can occur, especially with irregular meals, excessive alcohol, or increased physical activity without dietary adjustments. Warning Risk of severe hypoglycemia, particularly in elderly patients or those with irregular eating patterns. Not suitable for type 1 diabetes or diabetic ketoacidosis. Diatab may lose effectiveness over time as pancreatic function declines. Monitor blood glucose regularly and adjust dosage accordingly. Pregnancy and Breastfeeding Diatab is not recommended during pregnancy due to risk of neonatal hypoglycemia and birth defects. Insulin therapy is preferred for diabetes management during pregnancy. Glibenclamide passes into breast milk, so breastfeeding mothers should consult healthcare providers about alternative treatments. Interaction Increased hypoglycemia risk with alcohol, NSAIDs, or certain antibiotics Reduced effectiveness with corticosteroids, thiazide diuretics, or phenytoin Enhanced effects when combined with ACE inhibitors or beta-blockers Potential interaction with warfarin affecting blood clotting May be affected by certain antifungal medications Precaution Use cautiously in patients with kidney or liver impairment, elderly individuals, or those with irregular meal patterns. Monitor for signs of hypoglycemia including sweating, tremors, confusion, or rapid heartbeat. Avoid in patients with G6PD deficiency or sulfonamide allergies. Regular liver function monitoring may be required. Important Information Diatab is part of comprehensive diabetes management including diet, exercise, and regular monitoring. Carry glucose tablets or candy to treat hypoglycemia. Inform all healthcare providers about Diatab use before procedures or starting new medications. Store at room temperature away from moisture and heat. Regular follow-up appointments are essential for monitoring effectiveness and adjusting treatment. Product Image Gallery Customer questions & answers Have a question about this product? Your question * Name * Email * Notify me when answered. Recent Popular Unanswered There are no questions yet. Be the first to ask a question about this product. Selected with You in Mind Diamicron MR 60mg (Gliclazide) Tabs x30₦50,000.00Rated 0 out of 5 Diamicron MR 60mg is use for treatment of type 2... Add to cart Metaglomide Tablet 500/5mg x30₦15,000.00Rated 0 out of 5 Metaglomide Tablet is used for the management of type 2... 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